POLR2C Back

polymerase (RNA) II (DNA directed) polypeptide C, 33kDa

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of POLR2C
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.

Community Annotation of POLR2C Add / Edit POLR2C: Annotations

No community annotations yet for POLR2C.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POLR2C is highly significantly mutated in
(none)
POLR2C is significantly mutated in
(none)
POLR2C is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for POLR2C