POLA1 Back

polymerase (DNA directed), alpha 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of POLA1
This gene encodes the catalytic subunit of DNA polymerase, which together with a regulatory and two primase subunits, forms the DNA polymerase alpha complex. The catalytic subunit plays an essential role in the initiation of DNA replication.

Community Annotation of POLA1 Add / Edit POLA1: Annotations

No community annotations yet for POLA1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POLA1 is highly significantly mutated in
(none)
POLA1 is significantly mutated in
(none)
POLA1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for POLA1