POGK Back

pogo transposable element with KRAB domain

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NCBI Description of POGK

The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POGK is highly significantly mutated in
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POGK is significantly mutated in
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POGK is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for POGK