PODXL Back

podocalyxin-like

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PODXL
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Community Annotation of PODXL Add / Edit PODXL: Annotations

No community annotations yet for PODXL.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PODXL is highly significantly mutated in
(none)
PODXL is significantly mutated in
(none)
PODXL is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PODXL