PNPLA4 Back

patatin-like phospholipase domain containing 4

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NCBI Description of PNPLA4
This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y.

Community Annotation of PNPLA4 Add / Edit PNPLA4: Annotations

No community annotations yet for PNPLA4.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PNPLA4 is highly significantly mutated in
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PNPLA4 is significantly mutated in
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PNPLA4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PNPLA4