PNPLA3 Back

patatin-like phospholipase domain containing 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PNPLA3
The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.

Community Annotation of PNPLA3 Add / Edit PNPLA3: Annotations

No community annotations yet for PNPLA3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PNPLA3 is highly significantly mutated in
(none)
PNPLA3 is significantly mutated in
(none)
PNPLA3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PNPLA3