PNPLA2 Back

patatin-like phospholipase domain containing 2

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NCBI Description of PNPLA2
This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy.

Community Annotation of PNPLA2 Add / Edit PNPLA2: Annotations

No community annotations yet for PNPLA2.
Sort mutations by: Tumor type  Mutation type  Position  
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PNPLA2 is highly significantly mutated in
(none)
PNPLA2 is significantly mutated in
(none)
PNPLA2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PNPLA2