PMPCB Back

peptidase (mitochondrial processing) beta

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NCBI Description of PMPCB

This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.

Community Annotation of PMPCB Add / Edit PMPCB: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PMPCB is highly significantly mutated in
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PMPCB is significantly mutated in
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PMPCB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PMPCB