PLRG1 Back

pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)

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NCBI Description of PLRG1

This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of PLRG1 Add / Edit PLRG1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PLRG1 is highly significantly mutated in
PLRG1 is significantly mutated in
PLRG1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PLRG1