PLK2 Back

polo-like kinase 2 (Drosophila)

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NCBI Description of PLK2

The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PLK2 Add / Edit PLK2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PLK2 is highly significantly mutated in
PLK2 is significantly mutated in
PLK2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PLK2