PLCD4 Back

phospholipase C, delta 4

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PLCD4
This gene encodes a member of the delta class of phospholipase C enzymes. Phospholipase C enzymes play a critical role in many cellular processes by hydrolyzing phosphatidylinositol 4,5-bisphosphate into two intracellular second messengers, inositol 1,4,5-trisphosphate and diacylglycerol. Expression of this gene may be a marker for cancer.

Community Annotation of PLCD4 Add / Edit PLCD4: Annotations

No community annotations yet for PLCD4.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PLCD4 is highly significantly mutated in
(none)
PLCD4 is significantly mutated in
(none)
PLCD4 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PLCD4