PLA2G7 Back

phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

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NCBI Description of PLA2G7

The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PLA2G7 is highly significantly mutated in
PLA2G7 is significantly mutated in
PLA2G7 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PLA2G7