PLA2G4B Back

phospholipase A2, group IVB (cytosolic)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PLA2G4B
This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through transcripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic phospholipase A2 domains.

Community Annotation of PLA2G4B Add / Edit PLA2G4B: Annotations

No community annotations yet for PLA2G4B.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PLA2G4B is highly significantly mutated in
(none)
PLA2G4B is significantly mutated in
(none)
PLA2G4B is near significance in
(none)

Click on a tumor type to see its full list of significant genes.