PLA1A Back

phospholipase A1 member A

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NCBI Description of PLA1A

The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PLA1A Add / Edit PLA1A: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PLA1A is highly significantly mutated in
PLA1A is significantly mutated in
PLA1A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PLA1A