protein kinase (cAMP-dependent, catalytic) inhibitor alpha

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PKIA

The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported.

Community Annotation of PKIA Add / Edit PKIA: Annotations

No community annotations yet for PKIA.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PKIA is highly significantly mutated in
PKIA is significantly mutated in
PKIA is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PKIA