PKD1L1 Back

polycystic kidney disease 1 like 1

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NCBI Description of PKD1L1

This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PKD1L1 is highly significantly mutated in
PKD1L1 is significantly mutated in
PKD1L1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PKD1L1