PIWIL3 Back

piwi-like 3 (Drosophila)

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NCBI Description of PIWIL3
This gene encodes a member of the PIWI subfamily of Argonaute family proteins. This subfamily of proteins contains a PAZ domain, found in proteins involved in RNA-mediated gene silencing, and a C-terminal Piwi domain. The encoded protein is thought to function in maintenance of germline cells. Multiple transcript variants encoding different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PIWIL3 is highly significantly mutated in
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PIWIL3 is significantly mutated in
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PIWIL3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PIWIL3