PIWIL1 Back

piwi-like 1 (Drosophila)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PIWIL1
This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PIWIL1 Add / Edit PIWIL1: Annotations

No community annotations yet for PIWIL1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PIWIL1 is highly significantly mutated in
(none)
PIWIL1 is significantly mutated in
(none)
PIWIL1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PIWIL1