PITX1 Back

paired-like homeodomain 1

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NCBI Description of PITX1

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PITX1 is highly significantly mutated in
PITX1 is significantly mutated in
PITX1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PITX1