PITX1 Back

paired-like homeodomain 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PITX1
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.

Community Annotation of PITX1 Add / Edit PITX1: Annotations

No community annotations yet for PITX1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PITX1 is highly significantly mutated in
(none)
PITX1 is significantly mutated in
(none)
PITX1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PITX1