PIK3R2 Back

phosphoinositide-3-kinase, regulatory subunit 2 (beta)

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NCBI Description of PIK3R2

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PIK3R2 is highly significantly mutated in
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PIK3R2 is significantly mutated in
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PIK3R2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PIK3R2