PIK3CD Back

phosphoinositide-3-kinase, catalytic, delta polypeptide

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PIK3CD
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.

Community Annotation of PIK3CD Add / Edit PIK3CD: Annotations

No community annotations yet for PIK3CD.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PIK3CD is highly significantly mutated in
(none)
PIK3CD is significantly mutated in
(none)
PIK3CD is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PIK3CD