PIGW Back

phosphatidylinositol glycan anchor biosynthesis, class W

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NCBI Description of PIGW

Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).[supplied by OMIM, Mar 2008].

Community Annotation of PIGW Add / Edit PIGW: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PIGW is highly significantly mutated in
(none)
PIGW is significantly mutated in
(none)
PIGW is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PIGW