PIGQ Back

phosphatidylinositol glycan anchor biosynthesis, class Q

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NCBI Description of PIGQ
This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PIGQ Add / Edit PIGQ: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PIGQ is highly significantly mutated in
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PIGQ is significantly mutated in
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PIGQ is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PIGQ