PIGM Back

phosphatidylinositol glycan anchor biosynthesis, class M

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PIGM
This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum.

Community Annotation of PIGM Add / Edit PIGM: Annotations

No community annotations yet for PIGM.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PIGM is highly significantly mutated in
(none)
PIGM is significantly mutated in
(none)
PIGM is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PIGM