pleckstrin homology-like domain, family A, member 1

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NCBI Description of PHLDA1

This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PHLDA1 is highly significantly mutated in
PHLDA1 is significantly mutated in
PHLDA1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PHLDA1