PHF2 Back

PHD finger protein 2

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NCBI Description of PHF2

This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure.

Community Annotation of PHF2 Add / Edit PHF2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PHF2 is highly significantly mutated in
PHF2 is significantly mutated in
PHF2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PHF2