phosphatase and actin regulator 4

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NCBI Description of PHACTR4

This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PHACTR4 Add / Edit PHACTR4: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PHACTR4 is highly significantly mutated in
PHACTR4 is significantly mutated in
PHACTR4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PHACTR4