PGK2 Back

phosphoglycerate kinase 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PGK2

This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.

Community Annotation of PGK2 Add / Edit PGK2: Annotations

No community annotations yet for PGK2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PGK2 is highly significantly mutated in
(none)
PGK2 is significantly mutated in
(none)
PGK2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PGK2