PGK1 Back

phosphoglycerate kinase 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PGK1
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19.

Community Annotation of PGK1 Add / Edit PGK1: Annotations

No community annotations yet for PGK1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PGK1 is highly significantly mutated in
(none)
PGK1 is significantly mutated in
(none)
PGK1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PGK1