PGAP1 Back

post-GPI attachment to proteins 1

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NCBI Description of PGAP1

PGAP1 catalyzes the inositol deacylation of glycosylphosphatidylinositol (GPI) at an early step in GPI biosynthesis. Inositol deacylation is essential for the generation of mature GPI capable of attachment to proteins (Tanaka et al., 2004 [PubMed 14734546]).[supplied by OMIM, Mar 2008].

Community Annotation of PGAP1 Add / Edit PGAP1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PGAP1 is highly significantly mutated in
PGAP1 is significantly mutated in
PGAP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PGAP1