PFN3 Back

profilin 3

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NCBI Description of PFN3

The product of this gene belongs to the profilin family of proteins. This protein binds to actin and affects the structure of the cytoskeleton. It also may be involved in spermatogenesis. It is a single exon gene.

Community Annotation of PFN3 Add / Edit PFN3: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PFN3 is highly significantly mutated in
PFN3 is significantly mutated in
PFN3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PFN3