PFDN4 Back

prefoldin subunit 4

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NCBI Description of PFDN4
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PFDN4 is highly significantly mutated in
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PFDN4 is significantly mutated in
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PFDN4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PFDN4