PELP1 Back

proline, glutamate and leucine rich protein 1

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NCBI Description of PELP1
This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. Alternative splicing results in multiple transcript variants.

Community Annotation of PELP1 Add / Edit PELP1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PELP1 is highly significantly mutated in
(none)
PELP1 is significantly mutated in
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PELP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PELP1