PEF1 Back

penta-EF-hand domain containing 1

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NCBI Description of PEF1

This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PEF1 is highly significantly mutated in
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PEF1 is significantly mutated in
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PEF1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PEF1