PDXP Back

pyridoxal (pyridoxine, vitamin B6) phosphatase

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NCBI Description of PDXP
Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]).[supplied by OMIM, Mar 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PDXP is highly significantly mutated in
(none)
PDXP is significantly mutated in
(none)
PDXP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PDXP