PDS5A Back

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

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NCBI Description of PDS5A

The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PDS5A Add / Edit PDS5A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PDS5A is highly significantly mutated in
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PDS5A is significantly mutated in
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PDS5A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PDS5A