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NCBI Description of PDPN

This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of PDPN Add / Edit PDPN: Annotations

No community annotations yet for PDPN.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PDPN is highly significantly mutated in
PDPN is significantly mutated in
PDPN is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PDPN