PDIA6 Back

protein disulfide isomerase family A, member 6

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NCBI Description of PDIA6

Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 [PubMed 7590364]).[supplied by OMIM, Mar 2008].

Community Annotation of PDIA6 Add / Edit PDIA6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PDIA6 is highly significantly mutated in
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PDIA6 is significantly mutated in
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PDIA6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PDIA6