PDGFRL Back

platelet-derived growth factor receptor-like

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PDGFRL
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.

Community Annotation of PDGFRL Add / Edit PDGFRL: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PDGFRL is highly significantly mutated in
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PDGFRL is significantly mutated in
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PDGFRL is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PDGFRL