PDGFD Back

platelet derived growth factor D

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PDGFD
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.

Community Annotation of PDGFD Add / Edit PDGFD: Annotations

No community annotations yet for PDGFD.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PDGFD is highly significantly mutated in
(none)
PDGFD is significantly mutated in
(none)
PDGFD is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PDGFD