PDE9A Back

phosphodiesterase 9A

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NCBI Description of PDE9A
The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PDE9A is highly significantly mutated in
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PDE9A is significantly mutated in
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PDE9A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PDE9A