PDE6C Back

phosphodiesterase 6C, cGMP-specific, cone, alpha prime

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NCBI Description of PDE6C
This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4).

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PDE6C is highly significantly mutated in
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PDE6C is significantly mutated in
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PDE6C is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PDE6C