PDCD4 Back

programmed cell death 4 (neoplastic transformation inhibitor)

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NCBI Description of PDCD4

This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.

Community Annotation of PDCD4 Add / Edit PDCD4: Annotations

No community annotations yet for PDCD4.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PDCD4 is highly significantly mutated in
PDCD4 is significantly mutated in
PDCD4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PDCD4