PCBP3 Back

poly(rC) binding protein 3

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NCBI Description of PCBP3
This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Community Annotation of PCBP3 Add / Edit PCBP3: Annotations

No community annotations yet for PCBP3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PCBP3 is highly significantly mutated in
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PCBP3 is significantly mutated in
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PCBP3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PCBP3