PBK Back

PDZ binding kinase

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NCBI Description of PBK
This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

Community Annotation of PBK Add / Edit PBK: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PBK is highly significantly mutated in
(none)
PBK is significantly mutated in
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PBK is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PBK