PARP10 Back

poly (ADP-ribose) polymerase family, member 10

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NCBI Description of PARP10

Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008].

Community Annotation of PARP10 Add / Edit PARP10: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PARP10 is highly significantly mutated in
PARP10 is significantly mutated in
PARP10 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PARP10