PARD6B Back

par-6 partitioning defective 6 homolog beta (C. elegans)

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NCBI Description of PARD6B
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PARD6B is highly significantly mutated in
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PARD6B is significantly mutated in
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PARD6B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PARD6B