PANX1 Back

pannexin 1

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NCBI Description of PANX1

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Community Annotation of PANX1 Add / Edit PANX1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PANX1 is highly significantly mutated in
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PANX1 is significantly mutated in
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PANX1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PANX1