PANX1 Back

pannexin 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PANX1
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Community Annotation of PANX1 Add / Edit PANX1: Annotations

No community annotations yet for PANX1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PANX1 is highly significantly mutated in
(none)
PANX1 is significantly mutated in
(none)
PANX1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PANX1