PALB2 Back

partner and localizer of BRCA2

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NCBI Description of PALB2
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.

Community Annotation of PALB2 Add / Edit PALB2: Annotations

No community annotations yet for PALB2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PALB2 is highly significantly mutated in
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PALB2 is significantly mutated in
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PALB2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PALB2