PAIP1 Back

poly(A) binding protein interacting protein 1

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NCBI Description of PAIP1

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

Community Annotation of PAIP1 Add / Edit PAIP1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PAIP1 is highly significantly mutated in
PAIP1 is significantly mutated in
PAIP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PAIP1